Vad betyder Koagulaspositiv?

Innehållsförteckning:

1. Vad betyder Koagulaspositiv?
2. What is a coagulase negative staphylococcus?
3. How do you identify coagulase-negative staphylococci?
4. How many species of coagulase-negative staphylococcus are there?
5. What are the risk factors for coagulase-negative Staphylococcus aureus?

Vad betyder Koagulaspositiv?

Till skillnad från de flesta andra stafylokockarter är S. aureus koagulaspositiv. Det innebär att den kan bilda ett enzym som heter koagulas, vilket kan koagulera blodplasma.

What is a coagulase negative staphylococcus?

• Coagulase-negative staphylococci are gram-positive, aerobic organisms distinguished from the closely related Staphylococcus aureus by the group's inability to form coagulase, an enzyme that promotes thrombus formation via the conversion of fibrinogen into fibrin [2].

How do you identify coagulase-negative staphylococci?

• Clonal diversity among coagulase-negative staphylococci is discerned through multilocus sequence typing (MLST) of housekeeping genes and whole- genome sequencing with 70–90% accuracy in identifying specific staphylococcal species [1,2].

How many species of coagulase-negative staphylococcus are there?

• There are more than 45 recognized species of coagulase-negative staphylococci (CoNS). CoNS are gram-positive cocci that divide in irregular “grape-like” clusters and are differentiated from S. aureus by their inability to produce coagulase and coagulate rabbit plasma.

What are the risk factors for coagulase-negative Staphylococcus aureus?

• The main risk factor for coagulase-negative staphylococcal infection is a medical implant on which the organism can colonise, proliferate, and gain access to the systemic circulation [1,2,8]. Specific risk factors for coagulase-negative staphylococcal infection are: